PNMT (Phenylethanolamine-N-methyltransferase) polyclonal, anti-rat

Quantity: 50 µl

Background:
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.

Synonyms:
PNMT, PENT, PNMTase

Isotype: Guinea Pig Polyclonal

Immunogen:
Phenylethanolamine-N-methyltransferase from bovine adrenal medulla

Form: Serum containing 0.1% sodium azide

Specificity:
Absorption with 10-100 ?g immunogen per ml diluted antiserum abolishes the staining.

Reactivity: rat

Applications: Immunohistochemistry, suitable for frozen and paraffin sections

Working DIlution: 1:80 – 1:160 for immunohistochemistry (PAP)

Positive Control:
DEPC-fixed paraffin sections of rat adrenal gland

Storage: 2-8C for immediate use, or at -20C (aliquot)

References:
- Bjartell, A. et al. (1989) Regulatory Peptides 26: 27-34