PNP cDNA
€0.00
In stock
SKU
ATGD0131
Description
PNP encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.Alternative Names
Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PuNPConcentration
LyophilizedStorage: Store the plasmid at -20C.
PNP encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.Alternative Names
Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PuNPConcentration
LyophilizedStorage: Store the plasmid at -20C.
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