PNP polyclonal, anti-human, mouse

Background:
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

Synonyms: NP, PRO1837, PUNP

Cellular Location: Cytoplasm cytoskeleton

Immunogen:
Recombinant protein of human PNP

Gene Symbol: PNP

Gene ID: 4860

Swiss prot: P00491

Calculated MW: 32kDa

Recommended dilution:
WB 1:500-2000, IP 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.