PNPT1 Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.

Research Area: Cancer, Cell biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology

Synonyms:
3' 5' RNA exonuclease, COXPD13, DFNB70, old-35, OLD35, PNPASE, PNPase 1, Polynucleotide phosphorylase like protein, Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Immunogen: Synthetic peptide of human PNPT1

Swissprot: Q8TCS8
Gene Accession: NP_149100

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-49313/sc-49315/sc-99006