Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) [clone 3D3], anti-human, rabbit, rat

Description: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.Localization: cytoplasm, some membraneDilution: 50-200Positive Control: lymph nodeHIER: citrate pH6.0 or EDTA pH8.0Status: RUO