Podoplanin polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60406
Background:
Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.
Alternative Name:
Podoplanin, Aggrus, Glycoprotein 36, PA2.26 antigen, T1-alpha, T1A, PDPN, GP36, PSEC0003, PSEC0025
Application Dilution: WB: 1:500~1:1000
Specificity: Podoplanin polyclonal antibody detects endogenous levels of Podoplanin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Podoplanin.
MW: ~ 37 kDa
Swis Prot.: Q7L375
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Puromycin aminonucleoside nephrosis (PAN) is a rat model for human minimal change nephropathy. During PAN, severe proteinuria is induced that is paralleled by a reduced expression of a rat podocyte protein, named podoplanin. Podoplanin, also known as glycoprotein 38 (gp38) is a type I membrane protein. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes.
Alternative Name:
Podoplanin, Aggrus, Glycoprotein 36, PA2.26 antigen, T1-alpha, T1A, PDPN, GP36, PSEC0003, PSEC0025
Application Dilution: WB: 1:500~1:1000
Specificity: Podoplanin polyclonal antibody detects endogenous levels of Podoplanin protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Podoplanin.
MW: ~ 37 kDa
Swis Prot.: Q7L375
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review