PODXL (clone 5G6E6), anti-

Background:
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Research Area: Signal transduction, Cardiovascular, Cancer, Stem cells

Synonyms: PC, PDX, PCLP, Gp200, gp135, PCLP-1, PODXL1

Immunogen: Purified recombinant fragment of human PODXL (AA: Extra(23-172)) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage