Pokemon polyclonal, anti-human, mouse, rat

Protein Family: Translation Factors, Ubiquitins

Pathway and Disease: Cell Growth and Death, Immune System

Description:
Pokemon (POK erythroid myeloid ontogenic factor) plays a key role in the instruction of early lymphoid progenitors to develop into B lineage cells by repressing T-cell instructive Notch signals. Pokemon specifically represses the transcription of the CDKN2A gene, and efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Pokemon binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.

Alternate Names: Pokemon, POK erythroid myeloid ontogenic factor, Zinc finger and BTB domain-containing protein 7A, Leukemia/lymphoma-related factor, Factor that binds to inducer of short transcripts protein 1, Factor binding IST protein 1, FBI-1, HIV-1 1st-binding protein 1, TTF-I-interacting peptide 21, TIP21, POZ and Krueppel erythroid myeloid ontogenic factor, ZBTB7A

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: O95365

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term of human Pokemon.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.