POLD3 Polyclonal Antibody

Background:
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
POLD3, P66, P68, PPP1R128

Immunogen: Recombinant fusion protein of human POLD3 (NP_006582.1).

Swissprot: Q15054
Gene ID: 10714

Calculated MW: 39 kDa/46 kDa/51 kDa
Observed MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.