POLD4 Polyclonal Antibody

Background:
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
POLD4, POLDS, p12

Immunogen: Recombinant fusion protein of human POLD4 (NP_066996.3).

Swissprot: Q9HCU8
Gene ID: 57804

Calculated MW: 8 kDa/12 kDa
Observed MW: 20 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.