POLG2 Polyclonal Antibody

Background:
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
POLG2, HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB

Immunogen: Recombinant fusion protein of human POLG2 (NP_009146.2).

Swissprot: Q9UHN1
Gene ID: 11232

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:10-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.