POLK Polyclonal Antibody

Background:
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
POLK, DINB1, DINP, POLQ

Immunogen: Recombinant fusion protein of human POLK (NP_057302.1).

Swissprot: Q9UBT6
Gene ID: 51426

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.