POLR2B polyclonal, anti-human, mouse, rat

Background:
This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.

Synonyms: POL2RB, RPB2, hRPB140

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human POLR2B

Gene Symbol: POLR2B

Gene ID: 5431

Swiss prot: P30876

Calculated MW: 134kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.