POLR2B Polyclonal Antibody

Background:
This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
POLR2B, POL2RB, RPB2, hRPB140

Immunogen: Recombinant fusion protein of human POLR2B (NP_000929.1).

Swissprot: P30876
Gene ID: 5431

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.