POLR2E polyclonal, anti-human, mouse

Background:
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene.

Synonyms: RPABC1, RPB5, XAP4, hRPB25, hsRPB5

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human POLR2E

Gene Symbol: POLR2E

Gene ID: 5434

Swiss prot: P19388

Calculated MW: 25kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.