POLR2K polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60149
Background:
RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Alternative Name:
DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA polymerases I, II, and III subunit ABC4, ABC10-alpha, DNA-directed RNA polymerase II subunit K, RNA polymerase II 7.0 kDa subunit, RPB7.0, RPB10alpha, POLR2K
Application Dilution: WB: 1:500~1:1000
Specificity: POLR2K polyclonal antibody detects endogenous levels of POLR2K protein.
Immunogen:
A synthetic peptide corresponding to residues in Human POLR2K.
MW: ~ 7 kDa
Swis Prot.: P53803
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
Alternative Name:
DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA polymerases I, II, and III subunit ABC4, ABC10-alpha, DNA-directed RNA polymerase II subunit K, RNA polymerase II 7.0 kDa subunit, RPB7.0, RPB10alpha, POLR2K
Application Dilution: WB: 1:500~1:1000
Specificity: POLR2K polyclonal antibody detects endogenous levels of POLR2K protein.
Immunogen:
A synthetic peptide corresponding to residues in Human POLR2K.
MW: ~ 7 kDa
Swis Prot.: P53803
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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