POLR3K Polyclonal Antibody

Background:
This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.

Research Area: Epigenetics and Nuclear Signaling

Synonyms:
POLR3K, C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5

Immunogen: Recombinant fusion protein of human POLR3K (NP_057394.3).

Swissprot: Q9Y2Y1
Gene ID: 51728

Calculated MW: 12 kDa
Observed MW: 12 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.