Polyclonal AntibodyPC1 Polyclonal Antibody

Background:
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1

Immunogen: A synthetic peptide of human PABPC1 (NP_002559.2).

Swissprot: P11940
Gene ID: 26986

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.