PON1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Serum paraoxonase/arylesterase 1(PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1(paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein(HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Description:
Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 1 (PON1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
A esterase 1 antibody, A-esterase 1 antibody, Aromatic esterase 1 antibody, Arylesterase 1 antibody, Arylesterase B type antibody, ESA antibody, Esterase A antibody, K 45 antibody, K-45 antibody, MVCD5 antibody, Paraoxonase 1 antibody, Paraoxonase antibody, Paraoxonase B type antibody, Paraoxonase, plasma antibody, Paraoxonase1 antibody, PON 1 antibody, PON antibody, PON1 antibody, PON1_HUMAN antibody, Serum aryldiakylphosphatase antibody, Serum aryldialkylphosphatase 1 antibody, Serum paraoxonase/arylesterase 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human PON1(186-201aa FLDPYLQSWEMYLGLA), different from the related mouse and rat sequences by three amino acids.A synthetic peptide corresponding to a sequence in the middle region of human PON1(186-201aa FLDPYLQSWEMYLGLA), different from the related mouse and rat sequences by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.