PON1 polyclonal antibody, anti-human, mouse, rat

Background:
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.

Research Area: Cardiovascular, Cell biology, Metabolism, Neuroscience, Signal transduction

Synonyms: Serum paraoxonase/arylesterase 1 , PON 1, EC 3.1.1.2, EC 3.1.1.81, EC 3.1.8.1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1, PON 1, EC 3.1.1.2, EC 3.1.1.81, EC 3.1.8.1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year