PON2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
PON2 is an enzyme that in humans is encoded by the PON2 gene. This gene is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. 

Description:
Rabbit IgG polyclonal antibody for Serum paraoxonase/arylesterase 2 (PON2) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
A esterase 2 antibody, A-esterase 2 antibody, Aromatic esterase 2 antibody, Paraoxonase 2 antibody, Paraoxonase nirs antibody, PON 2 antibody, PON2 antibody, PON2_HUMAN antibody, Serum aryldialkylphosphatase 2 antibody, Serum paraoxonase/arylesterase 2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human PON2(189-203aa FLKYLETYLNLHWAN), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.