PON2 polyclonal (Center), anti-human, mouse

PON2 polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP5760c
Catalog Number: AC-AP5760c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21504
Applications: IF, IHC-P, WB
Datasheet

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Background:
PON2 is a member of the paraoxonase gene family,which includes three known members located adjacent to each otheron the long arm of chromosome 7. The encoded protein isubiquitously expressed in human tissues, membrane-bound, and mayact as a cellular antioxidant, protecting cells from oxidativestress. Hydrolytic activity against acylhomoserine lactones,important bacterial quorum-sensing mediators, suggests the encodedprotein may also play a role in defense responses to pathogenicbacteria. Mutations in this gene may be associated with vasculardisease and a number of quantitative phenotypes related todiabetes.

Other Names:
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2

Target/Specificity:
This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the Central region of human PON2.

Antigen Region:
74-101

Antigen Type: Synthetic Peptide

Gene Name: PON2
Gene ID: 5445
Primary Accession: Q15165
NCBI Accession: NP_000296.2
Other Accession: NP_000296.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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