POP7 polyclonal, anti-human
€388.00
In stock
SKU
BS71112
Background:
Ribonuclease P (RNase P) and Ribonuclease MRP (RNase MRP) are small nuclear ribonucleoproteins (snRNPs) that act on RNA substrates in vitro. RNase P and RNase MRP, which accumulate in the nucleolus, have a similar RNA component and also have several protein subunits in common. RNase P, which consists of a complex of an RNA species, POP1, POP5 and at least seven Rpps, remove the 5’ leader sequences from precursor tRNA molecules. Rpp20 (ribonuclease P protein subunit p20), also known as POP7 (processing of precursor 7, ribonuclease P/MRP subunit) or RPP2, is a 140 amino acid nuclear protein that belongs to the histone-like Alba family and functions as a component of nuclear RNase P and RNase MRP ribonucleoproteins. The gene encoding Rpp20 maps to human chromosome 7q22.1 and mouse chromosome 5 G2.
Alternative Name:
RPP2, RPP20, 0610037N12Rik,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: POP7 polyclonal antibody detects endogenous levels of POP7 protein.
Immunogen:
Recombinant protein of human POP7.
MW: ~ 16 kDa
Swis Prot.: O75817
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ribonuclease P (RNase P) and Ribonuclease MRP (RNase MRP) are small nuclear ribonucleoproteins (snRNPs) that act on RNA substrates in vitro. RNase P and RNase MRP, which accumulate in the nucleolus, have a similar RNA component and also have several protein subunits in common. RNase P, which consists of a complex of an RNA species, POP1, POP5 and at least seven Rpps, remove the 5’ leader sequences from precursor tRNA molecules. Rpp20 (ribonuclease P protein subunit p20), also known as POP7 (processing of precursor 7, ribonuclease P/MRP subunit) or RPP2, is a 140 amino acid nuclear protein that belongs to the histone-like Alba family and functions as a component of nuclear RNase P and RNase MRP ribonucleoproteins. The gene encoding Rpp20 maps to human chromosome 7q22.1 and mouse chromosome 5 G2.
Alternative Name:
RPP2, RPP20, 0610037N12Rik,
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: POP7 polyclonal antibody detects endogenous levels of POP7 protein.
Immunogen:
Recombinant protein of human POP7.
MW: ~ 16 kDa
Swis Prot.: O75817
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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