PORCN polyclonal, anti-mouse, rat

Background:
This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Synonyms: DHOF, FODH, MG61, PORC, PPN

Cellular Location: Endoplasmic reticulum membrane Multi-pass membrane protein

Immunogen:
Recombinant protein of human PORCN

Gene Symbol: PORCN

Gene ID: 64840

Swiss prot: Q9H237

Calculated MW: 52kDa

Recommended dilution:
WB 1:500-1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.