POT1 polyclonal, anti-human, mouse, rat

Background:
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Synonyms: CMM10, GLM9, HPOT1

Cellular Location: Chromosome Nucleus telomere

Immunogen:
Recombinant protein of human POT1

Gene Symbol: POT1

Gene ID: 25913

Swiss prot: Q9NUX5

Calculated MW: 71kDa

Recommended dilution:
WB 1:200-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.