POT1 Polyclonal Antibody

Background:
protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

Alternative Names:
POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein

Immunogen: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 70

GeneID: POT1

Storage: -20°C/1 year

NOTE: For Research Use Only