POTE-14/22 polyclonal antibody, anti-human
€0.00
In stock
SKU
BT-AP07336
Catalog Number: BT-AP07336
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human
Application(s): WB, IHC-p, ELISA
Datasheet
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Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: human
Application(s): WB, IHC-p, ELISA
Datasheet
Request Information
Background:
POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.
Research Area: Epigenetics and Nuclear Signaling
Synonyms: POTEH, A26C3, ACTBL1, POTE22, POTE ankyrin domain family member H, ANKRD26-like family C member 3, Prostate, ovary, testis-expressed protein on chromosome 22, POTE-22, POTEG, A26C2, POTE14, POTE anky
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.
Research Area: Epigenetics and Nuclear Signaling
Synonyms: POTEH, A26C3, ACTBL1, POTE22, POTE ankyrin domain family member H, ANKRD26-like family C member 3, Prostate, ovary, testis-expressed protein on chromosome 22, POTE-22, POTEG, A26C2, POTE14, POTE anky
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Storage:
-20°C for 1 year
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