POU3F2 polyclonal (Center), anti-human

POU3F2 polyclonal (Center), anti-human

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In stock
SKU
AC-AP16803C
Catalog Number: AC-AP16803C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36304
Applications: WB
Datasheet

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Background:
POU3F2 belongs to a large family of transcription factorsthat bind to the octameric DNA sequence ATGCAAAT. Most of theseproteins share a highly homologous region, referred to as the POUdomain, that occurs in several mammalian transcription factors,including the octamer-binding proteins Oct1 (POU2F1; MIM 164175)and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1;MIM 173110). Class III POU genes are expressed predominantly in thecentral nervous system (CNS). It is likely that CNS-specifictranscription factors such as these play an important role inmammalian neurogenesis by regulating their diverse patterns of gene[removed]Schreiber et al., 1993 [PubMed 8441633]; Atanasoski etal., 1995 [PubMed 7601453]).

Other Names:
POU domain, class 3, transcription factor 2, Brain-specific homeobox/POU domain protein 2, Brain-2, Brn-2, Nervous system-specific octamer-binding transcription factor N-Oct-3, Octamer-binding protein 7, Oct-7, Octamer-binding transcription factor 7, OTF-7, POU3F2, BRN2, OCT7, OTF7

Target/Specificity:
This POU3F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human POU3F2.

Antigen Region:
199-226

Antigen Type: Synthetic Peptide

Gene Name: POU3F2
Gene ID: 5454
Primary Accession: P20265
NCBI Accession: NP_005595.2
Other Accession: P56222; P31360; NP_005595.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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