POU5F1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Synonyms: OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human POU5F1

Gene Symbol: POU5F1

Gene ID: 5460

Swiss prot: Q01860

Calculated MW: 39kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.