PP1A / PPP1CA (N-terminus) (clone ), anti-human
€388.00
In stock
SKU
MB0084
Background:
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role. in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Alternative Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A
Application Dilution: WB: 1:1000, ICC: 1:200~400, IHC: 1:500
Specificity: This antibody detects endogenous levels of PP1A (N-terminus) and does not cross-react with related proteins
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human PP1A / PPP1CA.
MW: Predicted band size: 38KDa , Observed band size: 38KDa
Swis Prot.: P62136
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role. in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Alternative Name:
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, PP-1A, PPP1CA, PPP1A
Application Dilution: WB: 1:1000, ICC: 1:200~400, IHC: 1:500
Specificity: This antibody detects endogenous levels of PP1A (N-terminus) and does not cross-react with related proteins
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human PP1A / PPP1CA.
MW: Predicted band size: 38KDa , Observed band size: 38KDa
Swis Prot.: P62136
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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