PP2A-alpha polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
The catalytic subunit of human protein phosphatase 2A (PPP2CA) encodes a 309-amino acid polypeptide. It is localized to chromosome 5. The gene (approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue (Leu309) of protein serine/threonine phosphatase 2A catalytic subunit (PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.

Description:
Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
PP2A alpha antibody, PP2A-alpha antibody, PP2AA_HUMAN antibody, PP2Aalpha antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, PPP2CA antibody, Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform antibody, Protein phosphatase 2 catalytic subunit alpha isoform antibody, Protein phosphatase 2, catalytic subunit, alpha isozyme antibody, Protein phosphatase 2A catalytic subunit, alpha isoform antibody, Replication protein C antibody, RP C antibody, RP-C antibody, RPC antibody, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309). Human PP2A-alpha shares 100% amino acid (aa) sequence identity with both mouse and rat PP2A-alpha.E.coli-derived human PP2A-alpha recombinant protein (Position: M1-L309). Human PP2A-alpha shares 100% amino acid (aa) sequence identity with both mouse and rat PP2A-alpha.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
PP2A-alpha shares 100% cross reactivity with PPP2CB.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.