PP2A polyclonal, anti-human, mouse, rat

Protein Family: Enzymes

Pathway and Disease: Translation, Signal Transduction, Cell Growth and Death, Cell Communication, Nervous and Sensory Systems, Infectious Diseases

Description:
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A) can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I.

Alternate Names: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, RP-C, PPP2CA

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; ICC: 1:100-1:500

Accession No.: P67775

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PP2A.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.