PP2A polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
The catalytic subunit of human protein phosphatase 2A(PPP2CA) encodes a 309-amino acid polypeptide.It is localized to chromosome 5. The gene(approximately 30 kbp) is composed of seven exons and six introns. It is predicted to be important for phosphatase enzymatic activity. Methylation of the C-terminal leucine residue(Leu309) of protein serine/threonine phosphatase 2A catalytic subunit(PP2AC) is known to regulate catalytic activity in vitro. Furthermore, PP2A has a fundamental role in cardiac function, and suggests that disturbances in protein phosphatase expression and activity may cause or exacerbate the course of cardiac diseases.

Description:
Rabbit IgG polyclonal antibody for Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
PP2A alpha antibody, PP2A-alpha antibody, PP2AA_HUMAN antibody, PP2Aalpha antibody, PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, PPP2CA antibody, Protein phosphatase 2(formerly 2A) catalytic subunit alpha isoform antibody, Protein phosphatase 2 catalytic subunit alpha isoform antibody, Protein phosphatase 2, catalytic subunit, alpha isozyme antibody, Protein phosphatase 2A catalytic subunit, alpha isoform antibody, Replication protein C antibody, RP C antibody, RP-C antibody, RPC antibody, Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform antibody, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A(6-20aa FTKELDQWIEQLNEC), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human PP2A(6-20aa FTKELDQWIEQLNEC), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.