PP2Ac polyclonal, anti-human, mouse, rat
€422.00
In stock
SKU
250526
Catalog Nr.: 250526
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: Transcription Factors
Pathway and Disease: Cell Growth and Death, Cancers, Transcription
Description:
PP2Ac is a protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex plays a role in dephosphorylation and regulation of HDAC3, and negatively regulates CDK1 activity in interphase.
Alternate Names: PP4C, Serine/threonine-protein phosphatase 4 catalytic subunit, Pp4, Protein phosphatase X, PP-X, PPP4C
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P60510
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PP2Ac.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Ren W et al. 2016. Cancer Lett. 375(2): 209-20. PMID 26965998.
Pathway and Disease: Cell Growth and Death, Cancers, Transcription
Description:
PP2Ac is a protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex plays a role in dephosphorylation and regulation of HDAC3, and negatively regulates CDK1 activity in interphase.
Alternate Names: PP4C, Serine/threonine-protein phosphatase 4 catalytic subunit, Pp4, Protein phosphatase X, PP-X, PPP4C
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: P60510
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PP2Ac.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Ren W et al. 2016. Cancer Lett. 375(2): 209-20. PMID 26965998.
| Is Featured? | No |
|---|
Write Your Own Review