PP2Cε Polyclonal Antibody

Background:
protein phosphatase, Mg2+/Mn2+ dependent 1L(PPM1L) Homo sapiens The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Alternative Names:
PPM1L, PP2CE, Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon

Immunogen: The antiserum was produced against synthesized peptide derived from human PPM1L. AA range:119-168

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 48

GeneID: PPM1L

Storage: -20°C/1 year

NOTE: For Research Use Only