PPAN Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13950b
Background:
The protein encoded by this gene is an evolutionarilyconserved protein similar to yeast SSF1 as well as to the geneproduct of the Drosophila gene peter pan (ppan). SSF1 is known tobe involved in the second step of mRNA splicing. Both SSF1 and ppanare essential for cell growth and proliferation. Exogenousexpression of this gene was reported to reduce theanchorage-independent growth of some tumor cells. Read-throughtranscription of this gene with P2RY11/P2Y(11), an adjacentdownstream gene that encodes an ATP receptor, has been found. Theseread-through transcripts are ubiquitously present and up-regulatedduring granulocyte differentiation.
Other Names:
Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13950b was selected from the C-term region of PPAN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PPAN
Gene ID: 56342;692312
Primary Accession: Q9NQ55
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is an evolutionarilyconserved protein similar to yeast SSF1 as well as to the geneproduct of the Drosophila gene peter pan (ppan). SSF1 is known tobe involved in the second step of mRNA splicing. Both SSF1 and ppanare essential for cell growth and proliferation. Exogenousexpression of this gene was reported to reduce theanchorage-independent growth of some tumor cells. Read-throughtranscription of this gene with P2RY11/P2Y(11), an adjacentdownstream gene that encodes an ATP receptor, has been found. Theseread-through transcripts are ubiquitously present and up-regulatedduring granulocyte differentiation.
Other Names:
Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13950b was selected from the C-term region of PPAN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: PPAN
Gene ID: 56342;692312
Primary Accession: Q9NQ55
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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