PPAN polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13950b
Catalog Number: AC-AP13950b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24194
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24194
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Other Names:
Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1
Target/Specificity:
This PPAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human PPAN.
Antigen Region:
422-450
Antigen Type: Synthetic Peptide
Gene Name: PPAN
Gene ID: 56342;692312
Primary Accession: Q9NQ55
NCBI Accession: NP_001035754.1;NP_001185619.1;NP_064615.3
Other Accession: NP_001035754.1;NP_064615.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Other Names:
Suppressor of SWI4 1 homolog, Ssf-1, Brix domain-containing protein 3, Peter Pan homolog, PPAN, BXDC3, SSF1
Target/Specificity:
This PPAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human PPAN.
Antigen Region:
422-450
Antigen Type: Synthetic Peptide
Gene Name: PPAN
Gene ID: 56342;692312
Primary Accession: Q9NQ55
NCBI Accession: NP_001035754.1;NP_001185619.1;NP_064615.3
Other Accession: NP_001035754.1;NP_064615.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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