PPAPDC2 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254186
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Alternate Names: PPAPDC2, Phosphatidic acid phosphatase type 2 domain containing 2, PSD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_982278
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PPAPDC2.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Alternate Names: PPAPDC2, Phosphatidic acid phosphatase type 2 domain containing 2, PSD
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_982278
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human PPAPDC2.
Format: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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