PPAR-delta polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels, Transcription Factors

Pathway and Disease: Energy Metabolism

Description:
Peroxisome proliferator activated receptor delta (PPAR- delta, PPAR-beta, Nuclear hormone recptor 1, NUCI1) binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promotor element in the gene for acyl-CoA oxidase and activates its transcription. PPAR- delta controls the peroxisomal beta-oxidation pathway of fatty acids, belongs to the nuclear hormone receptor NR1 subfamily, and contains 1 nuclear receptor DNA-binding domain.

Alternate Names: PPAR-delta, Peroxisome proliferator-activated receptor delta, PPAR-beta, Nuclear receptor subfamily 1 group C member 2, Nuclear hormone receptor 1, NUC1, NUCI, PPARD

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: Q03181

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PPAR-delta.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.