PPARA Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12910c
Background:
Peroxisome proliferators include hypolipidemic drugs,herbicides, leukotriene antagonists, and plasticizers; this termarises because they induce an increase in the size and number ofperoxisomes. Peroxisomes are subcellular organelles found in plantsand animals that contain enzymes for respiration and forcholesterol and lipid metabolism. The action of peroxisomeproliferators is thought to be mediated via specific receptors,called PPARs, which belong to the steroid hormone receptorsuperfamily. PPARs affect the expression of target genes involvedin cell proliferation, cell differentiation and in immune andinflammation responses. Three closely related subtypes (alpha,beta/delta, and gamma) have been identified. This gene encodes thesubtype PPAR-alpha, which is a nuclear transcription factor.Multiple alternatively spliced transcript variants have beendescribed for this gene, although the full-length nature of onlytwo has been determined.
Other Names:
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR
Gene Name: PPARA
Gene ID: 5465
Primary Accession: Q07869
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Peroxisome proliferators include hypolipidemic drugs,herbicides, leukotriene antagonists, and plasticizers; this termarises because they induce an increase in the size and number ofperoxisomes. Peroxisomes are subcellular organelles found in plantsand animals that contain enzymes for respiration and forcholesterol and lipid metabolism. The action of peroxisomeproliferators is thought to be mediated via specific receptors,called PPARs, which belong to the steroid hormone receptorsuperfamily. PPARs affect the expression of target genes involvedin cell proliferation, cell differentiation and in immune andinflammation responses. Three closely related subtypes (alpha,beta/delta, and gamma) have been identified. This gene encodes thesubtype PPAR-alpha, which is a nuclear transcription factor.Multiple alternatively spliced transcript variants have beendescribed for this gene, although the full-length nature of onlytwo has been determined.
Other Names:
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR
Gene Name: PPARA
Gene ID: 5465
Primary Accession: Q07869
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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