PPARA monoclonal, anti-human, mouse

PPARA monoclonal, anti-human, mouse

€0.00
In stock
SKU
AC-AM8425b
Catalog Number: AC-AM8425b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,κ
Clone Name: 1331CT894.186.143
Applications: WB, IHC-P, IF, FC
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Background:
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

Other Names:
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR

Target/Specificity:
This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.

Antigen Region:
1-468

Antigen Type: Recombinant Protein

Gene Name: PPARA
Gene ID: 5465
Primary Accession: Q07869
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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