PPARA polyclonal (Center), anti-mouse
€0.00
In stock
SKU
AC-AP12910c
Catalog Number: AC-AP12910c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21340
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21340
Applications: FC, WB
Datasheet
Request Information
Background:
Peroxisome proliferators include hypolipidemic drugs,herbicides, leukotriene antagonists, and plasticizers; this termarises because they induce an increase in the size and number ofperoxisomes. Peroxisomes are subcellular organelles found in plantsand animals that contain enzymes for respiration and forcholesterol and lipid metabolism. The action of peroxisomeproliferators is thought to be mediated via specific receptors,called PPARs, which belong to the steroid hormone receptorsuperfamily. PPARs affect the expression of target genes involvedin cell proliferation, cell differentiation and in immune andinflammation responses. Three closely related subtypes (alpha,beta/delta, and gamma) have been identified. This gene encodes thesubtype PPAR-alpha, which is a nuclear transcription factor.Multiple alternatively spliced transcript variants have beendescribed for this gene, although the full-length nature of onlytwo has been determined.
Other Names:
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR
Target/Specificity:
This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.
Antigen Region:
153-181
Antigen Type: Synthetic Peptide
Gene Name: PPARA
Gene ID: 5465
Primary Accession: Q07869
NCBI Accession: NP_001001928.1;NP_005027.2
Other Accession: P37232; P37230; P23204; NP_005027.2; NP_001001928.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Peroxisome proliferators include hypolipidemic drugs,herbicides, leukotriene antagonists, and plasticizers; this termarises because they induce an increase in the size and number ofperoxisomes. Peroxisomes are subcellular organelles found in plantsand animals that contain enzymes for respiration and forcholesterol and lipid metabolism. The action of peroxisomeproliferators is thought to be mediated via specific receptors,called PPARs, which belong to the steroid hormone receptorsuperfamily. PPARs affect the expression of target genes involvedin cell proliferation, cell differentiation and in immune andinflammation responses. Three closely related subtypes (alpha,beta/delta, and gamma) have been identified. This gene encodes thesubtype PPAR-alpha, which is a nuclear transcription factor.Multiple alternatively spliced transcript variants have beendescribed for this gene, although the full-length nature of onlytwo has been determined.
Other Names:
Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR
Target/Specificity:
This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.
Antigen Region:
153-181
Antigen Type: Synthetic Peptide
Gene Name: PPARA
Gene ID: 5465
Primary Accession: Q07869
NCBI Accession: NP_001001928.1;NP_005027.2
Other Accession: P37232; P37230; P23204; NP_005027.2; NP_001001928.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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