PPARγ (clone 3G3-E2-H10), anti-transfected

Background:
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008].

Synonyms: CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma

Cellular Location: Cytoplasm Nucleus

Immunogen:
Purified recombinant human PPARγprotein fragments expressed in E.coli.

Gene Symbol: PPARγ

Gene ID: 5468

Swiss prot: P37231

Calculated MW: 53/57kDa

Recommended dilution:
WB 1:500

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.