PPARGC1A antibody (clone 3B5), anti-human
€435.00
In stock
SKU
AC-AT3396a
Catalog Number: AC-AT3396a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: IF, E
Request Information AC-AT3396a">Request Information
Background:
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Other Names:
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6, PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Antigen Type:
Recombinant Protein
Gene Name: PPARGC1A
Gene ID: 10891
NCBI Accession: NP_037393.1
Primary Accession: Q9UBK2
Other Accession: NM_013261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Other Names:
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6, PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Antigen Type:
Recombinant Protein
Gene Name: PPARGC1A
Gene ID: 10891
NCBI Accession: NP_037393.1
Primary Accession: Q9UBK2
Other Accession: NM_013261
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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