PPARGC1B (clone 6C3F6), anti-human

PPARGC1B (clone 6C3F6), anti-human

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In stock
SKU
BT-MCA2023
Catalog Number: BT-MCA2023
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): FCM
Datasheet
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Background:
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Cardiovascular, Epigenetics and nuclear signaling, Metabolism, Signal transduction

Synonyms: PERC, ERRL1, PGC1B, PGC-1(beta)

Immunogen: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage
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