PPARGC1B Polyclonal Antibody

Background:
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Signal transduction

Synonyms:
PERC, peroxisome proliferative activated receptor, gamma, coactivator 1, , peroxisome proliferator-activated receptor gamma coactivator 1 beta, Peroxisome proliferator-activated receptor gamma coactivator 1-beta, peroxisome proliferator-activated receptor gamma, coactivator 1 beta, PGC-1(beta), PGC-1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC1, PPAR gamma coactivator-1beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1, Ppargc1b, PRGC2

Immunogen: Synthetic peptide of human PPARGC1B

Swissprot: Q86YN6
Gene Accession: NP_001166169

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-67286/sc-67285