PPAT Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.

Research Area: Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
Amidophosphoribosyltransferase [Precursor], Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphatate amidotransferase, Glutamine phosphoribosylpyrophosphate amidotransferase, Glutamine PRPP amidotransferase, GPAT, Phosphoribosyl pyrophosphate amidotransferase, Ppat, PRAT, PUR1

Immunogen: Recombinant protein of human PPAT

Swissprot: Q06203
Gene Accession: BC004200

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-130698/sc-292403