PPFIA1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71528
Background:
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alternative Name:
LIP1, LIP.1, LIPRIN,
Application Dilution: WB : 1:500 - 1:2000
Specificity: PPFIA1 polyclonal antibody detects endogenous levels of PPFIA1 protein.
Immunogen:
Recombinant protein of human PPFIA1
MW: Predicted band size: 132 kDa, Observed band size: Refer to Figures
Swis Prot.: Q13136
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alternative Name:
LIP1, LIP.1, LIPRIN,
Application Dilution: WB : 1:500 - 1:2000
Specificity: PPFIA1 polyclonal antibody detects endogenous levels of PPFIA1 protein.
Immunogen:
Recombinant protein of human PPFIA1
MW: Predicted band size: 132 kDa, Observed band size: Refer to Figures
Swis Prot.: Q13136
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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