PPFIBP1 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17453c
Background:
The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. It has been proposedthat liprins are multivalent proteins that form complex structuresand act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases. This protein was found to interactwith S100A4, a calcium-binding protein related to tumorinvasiveness and metastasis. In vitro experiment demonstrated thatthe interaction inhibited the phosphorylation of this protein byprotein kinase C and protein kinase CK2. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.
Other Names:
Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1, hSGT2, PPFIBP1, KIAA1230
Gene Name: PPFIBP1
Gene ID: 8496
Primary Accession: Q86W92
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. It has been proposedthat liprins are multivalent proteins that form complex structuresand act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases. This protein was found to interactwith S100A4, a calcium-binding protein related to tumorinvasiveness and metastasis. In vitro experiment demonstrated thatthe interaction inhibited the phosphorylation of this protein byprotein kinase C and protein kinase CK2. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.
Other Names:
Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1, hSGT2, PPFIBP1, KIAA1230
Gene Name: PPFIBP1
Gene ID: 8496
Primary Accession: Q86W92
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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