PPL polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Synonyms: PPL

Cellular Location: Cell junction Cell membrane Cytoplasm Mitochondrion Nucleus cytoskeleton desmosome

Immunogen:
Recombinant protein of human PPL

Gene Symbol: PPL

Gene ID: 5493

Swiss prot: O60437

Calculated MW: 205kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.